Re: Minocycline

From: dali (weeble_at_wabble.com)
Date: 12/19/04


Date: Sun, 19 Dec 2004 20:43:03 GMT

On Sat, 18 Dec 2004 20:12:11 +0100, Martijn <Kw3Ls@hotmail.com> wrote:

>CNS infection
>Pharmacokinetically, minocycline and doxycycline are both highly
>lipid-soluble. However, compared with conventional tetracycline,
>minocycline is ten times more lipid-soluble whereas doxycycline is only
>five times more lipid-soluble. The clinical importance of this
>characteristic is that minocycline has particularly good tissue
>penetration and excellent CNS penetration; although doxycycline does
>penetrate the CNS, it does not do so to the degree that is achievable
>with minocycline."

I've heard good things about this abx. They gave it to rheumatoid
arthrits patients and it improved their symptoms. even cured many.
Then steroids came along.


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