2005: Therapy of Lyme disease depends on the age of the child and stage of the disease.
- From: "CaliforniaLyme" <CaliforniaLyme@xxxxxx>
- Date: 7 Jul 2005 13:09:27 -0700
1: Paediatr Drugs. 2005;7(3):163-176. Related Articles, Links
Tick-Borne Infections in Children : Epidemiology, Clinical
Manifestations, and Optimal Management Strategies.
Buckingham SC.
Department of Pediatrics, Division of Infectious Disease, University of
Tennessee Health Science Center and Children's Foundation Research
Center at Le Bonheur Children's Medical Center, Memphis, Tennessee,
USA.
Ticks can transmit bacterial, protozoal, and viral infections to
humans. Specific therapy is available for several of these infections.
Doxycycline is the antimicrobial treatment of choice for all patients,
regardless of age, with Rocky Mountain spotted fever, human monocytic
ehrlichiosis, or human granulocytic ehrlichiosis. Chloramphenicol has
been used to treat these infections in children but is demonstrably
inferior to doxycycline. In patients with Mediterranean spotted fever,
doxycycline, chloramphenicol, and newer macrolides all appear to be
effective therapies. Therapy of Lyme disease depends on the age of the
child and stage of the disease. For early localized disease,
amoxicillin (for those aged <8 years) or doxycycline (for those aged
>/=8 years) is effective. Doxycycline, penicillin V (phenoxymethylpenicillin) or penicillin G (benzylpenicillin) preparations, and erythromycin are all effective treatments for tick-borne relapsing fever. Hospitalized patients with tularemia should receive gentamicin or streptomycin. Doxycycline and ciprofloxacin have each been investigated for the treatment of tularemia in outpatients; however, these agents do not yet have established roles in the treatment of this disease in children. Combination therapy with clindamycin and quinine is preferred for children with babesiosis; the combination of azithromycin and atovaquone also appears promising. Ribavirin has been recently shown to markedly improve survival in patients with Crimean-Congo hemorrhagic fever. The role of antiviral therapy in the treatment of other tick-borne viral infections, including other hemorrhagic fevers and tick-borne encephalitis, is not yet defined.
PMID: 15977962 [PubMed - as supplied by publisher]
.
- Prev by Date: Re: Report: Drug firms spend most on lobbying
- Next by Date: Re: * NY TIMES TO RUN ARTICLE ON IGENEX *
- Previous by thread: 2003: babesiosis in Italy and Austria- NOT divergens!!!!!!!!!!!!!!!!
- Next by thread: 1993: Ehrlichiosis: A review of myelofibrosis in dogs.
- Index(es):
Relevant Pages
|
