Re: "With doxycycline 200 mg bid is more effective than 100 mg qid"
- From: "Frank de Groot" <franciad@xxxxxxxxx>
- Date: Sun, 16 Oct 2005 18:48:17 +0200
"Martijn" <Kw3Ls@xxxxxxxxxxx> wrote
>
> Donta prescribes tetracycline 1500mg/day. I wonder why there is such a
> huge difference between the dosage of doxycycline and tetracycline.
Tetracycline does not enter the blood-brain barrier, but it has greater
intracellural penetration than doxy.
Meaning, you would have to take around 5 grams of doxy to achieve the same
effect. It's not just tissue concentrations at work, also the MICS are
different.
With an LD50 of 2.5 g/kg in poultry, we can assume it's safe to take a few
grams in one go.
Doxy causes tissue damage so it's prudent to mix it with food.
.
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- "With doxycycline 200 mg bid is more effective than 100 mg qid"
- From: Martijn
- Re: "With doxycycline 200 mg bid is more effective than 100 mg qid"
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- Re: "With doxycycline 200 mg bid is more effective than 100 mg qid"
- From: Martijn
- Re: "With doxycycline 200 mg bid is more effective than 100 mg qid"
- From: Frank de Groot
- Re: "With doxycycline 200 mg bid is more effective than 100 mg qid"
- From: Martijn
- "With doxycycline 200 mg bid is more effective than 100 mg qid"
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