Re: Explainer on how to find out which strains are in California



I can understand that they might want to use OspA to characterize
relationships in strains/species, but why does it have any relevance to
testing. Isn't it true that OspA is downregulated in humans?

And another comment: the abstract which included Dattwyler had the
following passage, and I am wondering if this was, in fact, done in his
Prevue test.

"Specific and cross-reactive antigenic determinants need to be
considered in the design of improved immunodiagnostics for spirochetal
diseases."

It is my understranding that the Prevue test isn't any better, just
faster.

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