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Clin Infect Dis. 2003 Aug 15;37(4):528-32. Epub 2003 Jul 30. Related
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Asymptomatic infection with Borrelia burgdorferi.

Steere AC, Sikand VK, Schoen RT, Nowakowski J.

Division of Rheumatology/Immunology, Tufts University School of
Medicine, New England Medical Center, Boston, MA, USA.
asteere@xxxxxxxxxxxx

The natural history of asymptomatic seroconversion to Borrelia
burgdorferi has been unclear. We report here, on the basis of a post
hoc assessment, the frequency and outcome of asymptomatic
seroconversion to B. burgdorferi in participants of a large Lyme
disease vaccine trial. We show that infection with B. burgdorferi may
be asymptomatic but that asymptomatic infection is unusual in the
United States.

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