Denmark 2006: 2-tier approach w Western B confirmatory testing is not recomded since diagnostic specificity marginal
- From: "CaliforniaLyme" <CaliforniaLyme@xxxxxx>
- Date: 19 Nov 2006 11:31:53 -0800
1: Ugeskr Laeger. 2006 Aug 21;168(34):2805-7. Links
[Laboratory diagnosis of infection caused by Borrelia burgdorferi]
[Article in Danish]
Dessau RB, Bangsborg JM, Jensen TP, Hansen K, Lebech AM, Andersen CO.
Dansk Selskab for Klinisk Mikrobiologi, Dansk Selskab for
Infektionsmedicin. ram.dessau@xxxxxxxxxx
The laboratory diagnosis of Lyme disease in Denmark is reviewed with
recommendations for serological testing. In Denmark the laboratory
testing is performed with an ELISA technique. Most laboratories use an
assay based on purified flagella antigen. The two-tier approach with
Western Blot as confirmatory testing is not recommended since the
contribution to the diagnostic specificity is only marginal. Predictive
values of Lyme serology are presented, based on the estimated
prevalence of the different stages of Lyme disease in Denmark.
PMID: 16942701 [PubMed - indexed for MEDLINE]
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