2006: Motion-onset and pattern-reversal visual evoked potentials in diagnostics of neuroborreliosis.

1: J Clin Neurophysiol. 2006 Oct;23(5):416-20. Links
Motion-onset and pattern-reversal visual evoked potentials in
diagnostics of neuroborreliosis.
Kubova Z, Szanyi J, Langrova J, Kremlacek J, Kuba M, Honegr K.
Department of Pathophysiology, Charles University in Prague, Faculty of
Medicine in Hradec Kralove, Czech Republic. kubova@xxxxxxxxxxxx

Neuroborreliosis is a form of borreliosis that affects the central
and/or peripheral nervous system. Although it can mimic neurologic and
ophthalmologic disorders such as multiple sclerosis and optic neuritis,
visual evoked potential (VEP) examination is usually not used in
neuroborreliosis diagnostics. Combined VEP testing (pattern-reversal
VEPs and VEPs produced in response to linear and radial motion) was
performed in 81 patients with neuroborreliosis verified by laboratory
results (positive polymerase chain reaction or intrathecal antibodies
production). Thirty-four patients reported diplopia or blurred vision
related to borreliosis. In 33 (40%) patients the VEPs were delayed:
motion-onset VEPs were pathologic in 22 (27%) patients, reversal VEPs
in 5 (6%) patients, and both VEP types in 6 (7%) patients. The findings
suggest that VEP testing (especially the motion-onset VEP testing) can
confirm CNS involvement. Much higher sensitivity of motion-onset VEPs
in comparison with reversal VEPs can result from rather selective
(earlier) involvement of the magnocellular system or the dorsal stream
of the visual pathway.

PMID: 17016151 [PubMed - in process]

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