And you thought that Lymerx was wasn't ever going to be profitable

Klempner's latest from the current NEJM.


"Reservoir reduction may also be a viable strategy for the control of
infections for which the primary reservoir is not human. Tsao et al.2
have shown that vaccination of wild mice, a major reservoir of
Borrelia burgdorferi (the causative agent of Lyme disease), with
injected recombinant outer-surface protein A can significantly reduce
carriage of the organism by ticks in the subsequent year. Several
research groups are now developing mechanisms for delivering vaccines
to animal reservoirs, using oral baits. Oral baiting for wild-life
vaccination has proven very effective in combating the non-vectorborne
disease rabies. Other vectorborne infections for which wildlife
vaccination strategies are being tested include Yersinia pestis
(plague) and hantavirus."

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