Re: "Statins caused my kidney failure"
From: Robert (Robert_at_hotmail.com)
Date: 07/11/04
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Date: Sun, 11 Jul 2004 13:59:56 -0700
"Herman Rubin" <hrubin@odds.stat.purdue.edu> wrote in message
news:ccs5ji$51e8@odds.stat.purdue.edu...
> In article <10f0ibdlkqejtc7@corp.supernews.com>,
> Robert <Robert@hotmail.com> wrote:
>
> >"George Conklin" <nilknoc@earthlink.net> wrote in message > > What do you
> >mean no one noticed? How do you know about now?
>
> >> We know now because 40-50 years after treatment began, the proper
> >> research was done. I am surprised how gloriously ignorant you are.
>
> >How did they know then about doing the proper research about that
specific
> >problem that we know now?
> >That information was gained ONLY after 40-50 years of treatment
experience
> >AND our current understanding of cancer physiology. They didn't even have
> >tumor markers then so how in the hell would they have done the proper
> >research then? You totally don't have a clue. You are mixing up 50 years
ago
> >and today. Fifty years ago there was no HIV so why didn't they do the
> >research concerning the bad side effects in HIV infected women as far as
> >cervical and uterine cancer back then? Dahhh!!!!!!
>
> You are quite correct; we cannot wait until the "correct
> research" is being done. In fact, in too many cases, the
> FDA waits too long, and it is acting under pressure. The
> probabilistic analysis needed cannot be done except
> approximately, but those indoctrinated in the classical
> statistical religion are unable to understand this. Giving
> me the information that something was significant at a
> certain level, or the p-value, gives me some information,
> but not the relevant information.
>
> Here, we are given information about short term changes in
> small death rates from cardiovascular problems, but without
> considering all the relevant factors, and without adequate
> consideration of other problems. One thing always mishandled
> in medical studies is the question of those who drop out.
>
> I have seen the highly quoted summary paper, and I am not
> convinced. I will accept that lowering cholesterol to
> quite low levels will decrease cardiac incidents for most
> people in the short run. The rest is unclear.
You are not an extremist and have a reasonable approach to critical
thinking. I have no problem with your analysis. There are many things that
are not very clear.
"Life the way it really is- is a battle not between Bad and Good but between
Bad and Worse."
Joseph Brodsky NY Times Oct 1 1972
>
>
> --
> This address is for information only. I do not claim that these views
> are those of the Statistics Department or of Purdue University.
> Herman Rubin, Department of Statistics, Purdue University
> hrubin@stat.purdue.edu Phone: (765)494-6054 FAX: (765)494-0558
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