The word is finally getting out about rancid lipids/oxidized cholesterol.
- From: "montygram" <nazztrader@xxxxxxxxx>
- Date: 9 Jul 2005 20:49:13 -0700
In my local, mainstream newspaper, this article appeared a couple of
days ago. There are some minor problems with the reporter's
understanding and use of technical language, but overall the important
points are made:
Fat levels tied to heart disease
THE ASSOCIATED PRESS
July 7, 2005
New research gives the first solid evidence that a type of fat in the
bloodstream can trigger the earliest steps that lead to clogged blood
vessels, the top cause of heart attacks.
If further research bears this out, people might someday be tested for
this fat, just as they are for cholesterol now, to see if they're in
danger of having a heart attack. The study found that levels of the fat
strongly correlated with the risk of heart disease, especially in
people under age 60.
"It is an important study," said Judith Berliner, a professor of
medicine at the University of California, Los Angeles, who had no role
in the research but wrote an editorial accompanying it in today's New
England Journal of Medicine.
Doctors say the findings give people another reason to limit fat in
their diets.
No one really knows what causes the formation of blockages, which can
squeeze blood vessels shut and deprive the heart of nourishment.
"Most of the studies in the past have revolved around cholesterol," but
other factors also must be involved because cholesterol levels are
normal in many heart attack victims, Berliner said.
Scientists have long suspected that one such factor might be oxidized
phospholipids, a type of fat that's a major component of LDL or "bad
cholesterol." Research in animals has found that this fat, floating in
the bloodstream, contributes in many ways to blockage formation. The
new research, led by Dr. Sotirios Tsimikas at the University of
California, San Diego, is the first to show the same is true in people.
Tsimikas studied 504 people being tested for clogged arteries.
Among those 60 or younger, people with the highest levels of oxidized
phospholipids were three times more likely to have blockages than those
with the lowest levels.
Those who had high phospholipids and high cholesterol were at even
greater risk. Getting a measurement of the level of this fat must be
done separately from tests for total cholesterol and LDL.
More research of phospholipid levels in all types of people is needed,
said Dr. Sidney Smith, director of the center for cardiovascular
diseases at the University of North Carolina at Chapel Hill and past
president of the American Heart Association.
http://www.newsday.com/mynews/ny-hshart074333752jul07,0,1689927.story
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