Re: Flax oil, kefir, yogurt producing no immune system benefits



Mon, 23 Jan 2006 03:54:31 +0200 in article
<tl98t15u4d525u9ckgfsvk438o8r6psh7k@xxxxxxx> Matti Narkia
<narkia@xxxxxxxxx> wrote:

>Sat, 21 Jan 2006 08:46:21 GMT in article
><xxmAf.341$1n4.154@xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx> "Knack"
><zymatik@xxxxxxxxxxxxxxx> wrote:
>
>>Hi. I am age 51. For the past 15 months every morning I've been blending
>>high lignan flax seed oil with either yogurt or kefir as part of my
>>breakfast. And I've been keeping my daily intake of omega-6 fat approx equal
>>to my omega-3 fats intake. And I avoid sugar except for what is found in
>>about 6 different whole fruits every day. And I have 2 cups of green tea
>>every day, along with a cup of cocoa and 2 cups of rooibos. And every day I
>>also take 400 mg natural E-complex vitamin, 50 mg selenium, 1000 mg vitamin
>>ester-C, 100 mg CoQ10, 400 mg alpha-lipoic acid, 400 mg quercetin, 100 mg
>>MSM, plus individual garlic, cranberry, and grapeseed extract pills.
>>
>>Not to mention the healthy meals that I eat, that's a lot of daily
>>nutrients. I'm hoping that my continued use of them will help to prevent me
>>from some day getting cancer. However, that's not a realistic expectation as
>>last May they could not even prevent me from getting a persistent cold/flu
>>following an airline trip. Although I still continue to take all of the
>>above stuff, it certainly has been quite a disappointment so far.
>>
>You are raising two different and very large issues here: prevention of
>cancer and optimizing immune defence. You surely understand that it's
>only possible to scratch the surface of these topics here. There is some
>overlap in these topics, but the prevention of cancer it's not primarly
>an immune system issue. To prevent cancer you need first to have healthy
>life style: no smoking, no excessive alcohol, avoiding carcinogenic
>substances, controlling the weight, getting enough exercise, healthy
>diet etc.. Some of the supplements and food items you are taking may
>help (although you don't want to take 50 mg of selenium/d, you wouldn't
>live very long ;-)), but you may want to add for example broccoli and
>curcumin (from turmeric) just to to mention a couple more.
>
>Immune system cannot detect all cancers well enough and some cancers can
>make immune system ineffective. Although it's important to try to keep
>your immune system in good condition, there are many other ways to fight
>cancer. By avoiding carcinogens and using antioxidants you may be able
>to reduce the risk of cancer initiation phase. And by using natural
>cancer fighters, which cause apoptosis of cancer cells, prevent tumor
>angiogenesis etc., you may be able to reduce cancer growth rate and
>inhibit its promotion.
>
>An immune system, which cannot stop cancer, may still be able to fight
>off viral and bacterial infections.
>
>Many things can go wrong with immune system. One of the currently
>popular hypotheses is that imbalance between type 1 and type 2 T helper
>cells (Th1/Th2 imbalance) may play a role in many diseases. Often the
>problem is the dominance of Th2 cells. Some lactic acid bacteria, some
>herbs such as astragalus and propolis, and some vitamins and minerals
>and trace elements (zinc for example) may help to correct this
>imbalance.
>
>As for influenza and common cold, black elderberry extract such as
>Sambucol may help.
>
>
>References:
>
>Kidd P.
>Th1/Th2 balance: the hypothesis, its limitations, and implications
>for health and disease.
>Altern Med Rev. 2003 Aug;8(3):223-46. Review.
>PMID: 12946237 [PubMed - indexed for MEDLINE]
><http://www.thorne.com/altmedrev/.fulltext/8/3/223.pdf>
>
>CND: Balance the Th1/Th2 Immune System
><http://www.anapsid.org/cnd/diagnosis/cheneyis.html>
>
>Veckman V, Miettinen M, Matikainen S, Lande R, Giacomini E, Coccia EM,
>Julkunen I.
>Lactobacilli and streptococci induce inflammatory chemokine production
>in human macrophages that stimulates Th1 cell chemotaxis.
>J Leukoc Biol. 2003 Sep;74(3):395-402.
>PMID: 12949243 [PubMed - indexed for MEDLINE]
><http://www.jleukbio.org/cgi/content/abstract/74/3/395>
>
>Sudo N, Yu XN, Aiba Y, Oyama N, Sonoda J, Koga Y, Kubo C.
>An oral introduction of intestinal bacteria prevents the development of
>a long-term Th2-skewed immunological memory induced by neonatal
>antibiotic treatment in mice.
>Clin Exp Allergy. 2002 Jul;32(7):1112-6.
>PMID: 12100062 [PubMed - indexed for MEDLINE]
><http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12100062>
><http://www.blackwell-synergy.com/doi/abs/10.1046/j.1365-2222.2002.01430.x>
>
>Gill HS, Guarner F.
>Probiotics and human health: a clinical perspective.
>Postgrad Med J. 2004 Sep;80(947):516-26. Review.
>PMID: 15356352 [PubMed - indexed for MEDLINE]
><http://pmj.bmjjournals.com/cgi/content/full/80/947/516>
>
>Isolauri E, Sutas Y, Kankaanpaa P, Arvilommi H, Salminen S.
>Probiotics: effects on immunity.
>Am J Clin Nutr. 2001 Feb;73(2 Suppl):444S-450S. Review.
>PMID: 11157355 [PubMed - indexed for MEDLINE]
><http://www.ajcn.org/cgi/content/full/73/2/444S>
>
>Matsuzaki T, Chin J.
>Modulating immune responses with probiotic bacteria.
>Immunol Cell Biol. 2000 Feb;78(1):67-73.
>PMID: 10651931 [PubMed - indexed for MEDLINE]
><http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10651931>
>
>Yasui H, Shida K, Matsuzaki T, Yokokura T.
>Immunomodulatory function of lactic acid bacteria.
>Antonie Van Leeuwenhoek. 1999 Jul-Nov;76(1-4):383-9. Review.
>PMID: 10532394 [PubMed - indexed for MEDLINE]
><http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10532394>
>
>Watanabe T, Hotta C.
>Enhancement of host resistance to microbial infections in mice fed a
>high fat diet by Lactobacillus casei cells.
>Hiroshima J Med Sci. 1996 Jun;45(2):63-8.
>PMID: 8810133 [PubMed - indexed for MEDLINE]
><http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=881013>
>
>Watanabe T, Yamori T.
>Primary resistance induced in mice by Lactobacillus casei following
>infection with herpes simplex virus.
>Kansenshogaku Zasshi. 1989 Mar;63(3):182-8.
>PMID: 2475554 [PubMed - indexed for MEDLINE]
><http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=2475554>
>
>Watanabe T, Saito H.
>Protection of mice against herpes simplex virus infection by a
>Lactobacillus casei preparation (LC 9018) in combination with
>inactivated viral antigen.
>Microbiol Immunol. 1986;30(2):111-22.
>PMID: 3012292 [PubMed - indexed for MEDLINE]
><http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=3012292>
>
>Braat H, van den Brande J, van Tol E, Hommes D, Peppelenbosch M, van
>Deventer S.
>Lactobacillus rhamnosus induces peripheral hyporesponsiveness in
>stimulated CD4+ T cells via modulation of dendritic cell function.
>Am J Clin Nutr. 2004 Dec;80(6):1618-25.
>PMID: 15585777 [PubMed - in process]
><http://www.ajcn.org/cgi/content/abstract/80/6/1618>
>
>Noverr MC, Huffnagle GB.
>Does the microbiota regulate immune responses outside the gut?
>Trends Microbiol. 2004 Dec;12(12):562-8.
>PMID: 15539116 [PubMed - in process]
><http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15539116>
>
>Sudo N, Aiba Y, Oyama N, Yu XN, Matsunaga M, Koga Y, Kubo C.
>Dietary nucleic acid and intestinal microbiota synergistically
>promote a shift in the Th1/Th2 balance toward Th1-skewed immunity.
>Int Arch Allergy Immunol. 2004 Oct;135(2):132-5. Epub 2004 Sep 02.
>PMID: 15345911 [PubMed - indexed for MEDLINE]
><http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15345911>
>
>Pochard P, Gosset P, Grangette C, Andre C, Tonnel AB, Pestel J,
>Mercenier A.
>Lactic acid bacteria inhibit TH2 cytokine production by mononuclear
>cells from allergic patients.
>J Allergy Clin Immunol. 2002 Oct;110(4):617-23.
>PMID: 12373271 [PubMed - indexed for MEDLINE]
><http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=12373271>
>
>Dunne C, O'Mahony L, Murphy L, Thornton G, Morrissey D, O'Halloran S,
>Feeney M, Flynn S, Fitzgerald G, Daly C, Kiely B, O'Sullivan GC,
>Shanahan F, Collins JK.
>In vitro selection criteria for probiotic bacteria of human origin:
>correlation with in vivo findings.
>Am J Clin Nutr. 2001 Feb;73(2 Suppl):386S-392S. Review.
>PMID: 11157346 [PubMed - indexed for MEDLINE]
><http://www.ajcn.org/cgi/content/full/73/2/386S>
>
And here a recent study about Lactobacillus reuteri:

Tubelius P, Stan V, Zachrisson A.
Increasing work-place healthiness with the probiotic Lactobacillus
reuteri: A randomised, double-blind placebo-controlled study.
Environ Health. 2005 Nov 7;4(1):25 [Epub ahead of print]
PMID: 16274475 [PubMed - as supplied by publisher]
<http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=16274475>
<http://www.ehjournal.net/content/pdf/1476-069x-4-25.pdf>

Comments:

Probiotic May Reduce Sick Days From Work CME
Medscape Medical News, 2005 November 14.
<http://www.medscape.com/viewarticle/516801>

Less sick leave with Reuteri
Biogaia : BioGaia
<http://www.biogaia.se/?id=27862>



-Matti Narkia
.



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