Re: Shellfish allergy & Chondroiton?
- From: AB <ab@xxxxxxxxxxxx>
- Date: Mon, 05 Feb 2007 14:27:02 GMT
On Sun, 04 Feb 2007 11:48:47 GMT, GMCarter <fiar@xxxxxxxxxxx> wrote:
On Sat, 03 Feb 2007 16:09:53 GMT, AB <ab@xxxxxxxxxxxx> wrote:
Hi,
Having just found out I have the start of arthritis in an elbow, I'd
like to do what I can to keep it from progressing. I already take
Glucosamine, a vegetarian version. I know the combo of Glucosamine &
Chondroiton is more powerful than each alone, but having had an
allergy to shellfish, I'm hesitant to take the Chondroiton.
My question: can Chondroiton cause an allergic reaction in people
who have allergies to shellfish?
Actually, no but glucosamine might. It would appear that it is not
doing so in your case if you have been taking it for some time. Remain
alert. The good news, however, is that people with shrimp allergies
probably do NOT have any reaction to it (see abstract below).
Here:
http://www.anaphylaxis.org.uk/information/common_food_allergens.html
they note:
"Shellfish shell and skeleton derivatives
Although it is the flesh of shellfish that contains the allergen,
people with shellfish allergy are advised to avoid shellfish shells
and skeletons. Glucosamine, used in the treatment of arthritis, is
derived from the skeletons of shellfish and is unsuitable for people
with shellfish allergy. Chondroitin is a shellfish-free alternative.
Chitin, derived from shellfish shells, is used in commercial "fat
absorbers" such as Chitosan HD, and should be avoided. Moisturisers
can also contain shellfish-derived chitin. Some calcium supplements
may contain ground oyster shells. "
George M. Carter
***
Villacis J, Rice TR, Bucci LR, El-Dahr JM, Wild L, Demerell D, Soteres
D, Lehrer SB. Do shrimp-allergic individuals tolerate shrimp-derived
glucosamine? Clin Exp Allergy. 2006 Nov;36(11):1457-61.
Tulane University Health Sciences Center, Department of Clinical
Immunology, Allergy, and Rheumatology, New Orleans, LA 70112, USA.
BACKGROUND: There is concern that shrimp-allergic individuals may
react to glucosamine-containing products as shrimp shells are a major
source of glucosamine used for human consumption. OBJECTIVE: The
purpose of this study was to determine whether shrimp-allergic
individuals can tolerate therapeutic doses of glucosamine. METHODS:
Subjects with a history of shrimp allergy were recruited and tested
for both shrimp reactivity via a prick skin test and shrimp-specific
IgE by an ImmunoCAP assay. Fifteen subjects with positive skin tests
to shrimp and an ImmunoCAP class level of two or greater were selected
for a double-blind placebo-controlled food challenge (DBPCFC) using
glucosamine-chondroitin tablets containing 1,500 mg of synthetically
produced (control) or shrimp-derived glucosamine. Immediate reactions,
including changes in peak flow and blood pressure, and delayed
reactions (up to 24 h post-challenge) via questionnaire were noted and
assessed. RESULTS: All subjects tolerated 1,500 mg of both
shrimp-derived or synthetic glucosamine without incident of an
immediate hypersensitivity response. Peak flows and blood pressures
remained constant, and no subject had symptoms of a delayed reaction
24 h later. CONCLUSION: This study demonstrates that glucosamine
supplements from specific manufacturers do not contain clinically
relevant levels of shrimp allergen and therefore appear to pose no
threat to shrimp-allergic individuals.
Thanks for the information. Guess I take the vegetarian Glucosamine
because I found this out sometime in the past. Chondroitin seems OK,
so I'll try it.
.
- References:
- Shellfish allergy & Chondroiton?
- From: AB
- Re: Shellfish allergy & Chondroiton?
- From: GMCarter
- Shellfish allergy & Chondroiton?
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