Re: Deleterious metabolic effects of high-carbohydrate, sucrose-containing diets in patients with non-insulin-dependent diabetes mellitus.

On Feb 12, 4:19 pm, capm...@xxxxxxxxxxx wrote:
And this is news?

Nope. It is science. Interesting how you failed to recognize that.

TC




http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&;...
3544839&dopt=Citation

Deleterious metabolic effects of high-carbohydrate, sucrose-containing
diets in patients with non-insulin-dependent diabetes
mellitus.Coulston AM, Hollenbeck CB, Swislocki AL, Chen YD, Reaven
GM.
The effects of variations in dietary carbohydrate and fat intake on
various aspects of carbohydrate and lipid metabolism were studied in
patients with non-insulin-dependent diabetes mellitus (NIDDM). Two
test diets were utilized, and they were consumed in random order over
two 15-day periods. One diet was low in fat and high in carbohydrate,
and corresponded closely to recent recommendations made by the
American Diabetes Association (ADA), containing (as percent of total
calories) 20 percent protein, 20 percent fat, and 60 percent
carbohydrate, with 10 percent of total calories as sucrose. The other
diet contained 20 percent protein, 40 percent fat, and 40 percent
carbohydrate, with sucrose accounting for 3 percent of total calories.
Although plasma fasting glucose and insulin concentrations were
similar with both diets, incremental glucose and insulin responses
from 8 a.m. to 4 p.m. were higher (p less than 0.01), and mean (+/-
SEM) 24-hour urine glucose excretion was significantly greater (55 +/-
16 versus 26 +/- 4 g/24 hours p less than 0.02) in response to the low-
fat, high-carbohydrate diet. In addition, fasting and postprandial
triglyceride levels were increased (p less than 0.001 and p less than
0.05, respectively) and high-density lipoprotein (HDL) cholesterol
concentrations were reduced (p less than 0.02) when patients with
NIDDM ate the low-fat, high-carbohydrate diet. Finally, since low-
density lipoprotein (LDL) concentrations did not change with diet, the
HDL/LDL cholesterol ratio fell in response to the low-fat, high-
carbohydrate diet. These results document that low-fat, high-
carbohydrate diets, containing moderate amounts of sucrose, similar in
composition to the recommendations of the ADA, have deleterious
metabolic effects when consumed by patients with NIDDM for 15 days.
Until it can be shown that these untoward effects are evanescent, and
that long-term ingestion of similar diets will result in beneficial
metabolic changes, it seems prudent to avoid the use of low-fat, high-
carbohydrate diets containing moderate amounts of sucrose in patients
with NIDDM.

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