Re: high cholesterol has a genetic basis?

On Jun 18, 2:12 am, conrad <con...@xxxxxxxxxx> wrote:
I've heard that even though some people eat right
and exercise regularly, they still have high levels of
cholesterol. I'm looking to determine the validity
of this claim.

If you search for "familial hypercholesterolaemia" you'll find some.
The two broad defects are insufficient cell surface LDL receptors or
a defect in the apolipoprotein which binds to the LDL receptor. Either
way the LDL stays in the blood so levels increase over time. Rats with
an apolipoprotein disorder they will get high blood cholesterol even
on a fat-free diet.

MattLB


.

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