Arachidonic acid and the origin of cancer.

Here is just the latest of what is now a large professional literature
on this subject. This is molecular-level evidence (there is nothing
stronger, no "atomic level" evidence, for those of you who don't
realize this). You can do your own search on pubmed.com on this
subject, start with keywords like arachidonic cancer, ltb4 cancer, and
pge2 cancer.

ScientificWorldJournal. 2007 Sep 1;7:1413-21.

"The role of leukotriene receptor signaling in inflammation and
cancer."

Abstract:

"Leukotrienes (LTs) and prostaglandins (PGs) are metabolites of
arachidonic acid that play major roles in various inflammatory
conditions. The release of these mediators, by cells recruited to or
present at the site of inflammation, modulate/influence the magnitude
of the inflammatory response. A better understanding of eicosanoids
and how their receptors trigger intracellular signaling during
inflammatory conditions is helping to elucidate the well-known
connection between chronic inflammatory disease and neoplastic
transformation. In the current review, we summarize the role of LTs
and PGs in chronic inflammation and, in particular, we focus on recent
insights into the role of CysLT1 receptor signaling pathway. In
addition, we delineate how continuous CysLT1 receptor activation and
signaling can increase cell survival and proliferation as important
early steps toward oncogenicity."

Note that you don not have to have AA in your cells, and in fact this
is a recent development. You can go to my free site and read more
about this and related issues:

http://groups.msn.com/TheScientificDebateForum-

.

Quantcast