Re: Resveratrol dosage

On Jan 7, 11:06 am, JayDee <dopam...@xxxxxxxx> wrote: If I'm trying to
get the benefits of Resveratrol,
is taking a combo supplement with 30mg going to be sufficient?
Unfortunately, many of
the studies I've read do not specify dosages used. <<

This is quite the window .. and since they are showing such ..
druglike effects of these supplements / efficacy .. then one might
wonder if going the natural .. route might be more .. safe.
Iron restricted .. diet.

"87.5 to 875 milligrams were effective in this regard"

http://www.resveratrolnews.com/page77.htm


Researchers Show Resveratrol
Works In The Brain By Metal Chelating Effects


Researchers now convincingly show that, via its iron-chelating
effects, resveratrol is able to cross barriers that protect the brain
from entry of toxins (blood/brain barrier) and reduce oxidation
(spoilage) of fats and increase the activity of protective
antioxidant
enzymes in the brain of healthy rodents. The research has
application
for age-related brain disorders such as Alzheimer's and Parkinson's
disease.


Resveratrol decreased malondialdehyde (an end product of oxidation
of
fats) in brain tissues by -300%. Doses ranging (in human
equivalents)
from 87.5 to 875 milligrams were effective in this regard. Higher
doses were not more effective.


Resveratrol also significantly increased the activity of antioxidant
enzymes superoxide dismutase, catalase and peroxidase by 160%, 270%
and 210% (see above chart). The forms of most of these protective
enzymes were iron-controlling proteins, confirming that resveratrol's
primary action is via its ability to control metallic metals. Loose
(free) iron causes tissue damage in all forms of age-related brain
disease. While a relatively high dose of resveratrol was shown to
be
most effective (875 milligrams human equivalent dose), this was only
a
7-day study. It is expected that a life-long accumulation of iron in
brain tissues will require a high loading dose and a lower
maintenance
dose. The current fad of ultra-high dose resveratrol supplementation
may be beneficial initially, but lead to anemias over longer term
use. -Resveratrol News April 2007


Who loves ya.
Tom


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http://jesuswasavegetarian.7h.com


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I was taking a 325 mg Resveratrol supplement for a while, and recently
came across a few "combo" supplements that had significantly lower
dosages of Resveratrol (30mg) in combination with, in one case, 100 mg
grape seed extract, 25mg olive fruit extract, and 200mg green tea. In
other cases, I saw 100mg of Resveratrol combined with "OPC's".

If I'm trying to get the benefits of Resveratrol, is taking a combo
supplement with 30mg going to be sufficient? Unfortunately, many of
the studies I've read do not specify dosages used.

Thanks!

- JayDee

.

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