Re: Applied Nutrigenomics
- From: TC <tunderbar@xxxxxxxxxxx>
- Date: Wed, 12 Mar 2008 12:45:21 -0700 (PDT)
On Mar 10, 2:27 am, Taka <taka0...@xxxxxxxxx> wrote:
Applied Nutrigenomics
Where Genes and Food Come Together - Part 1
by Dr. John M. Berardi, PhD, CSCS
First published atwww.t-nation.com
Nutrigenomics: The study of how genes and nutrients interact.
Until recently, I knew this field of science was an exciting area that
would someday change the future of nutrition, medicine, and more.
However, in my mind all this crazy gene-nutrient stuff was still
wrapped up in mystery. It was the stuff futurists hypothesized about
rather than the stuff physicians, nutritionists, and health experts
could use every day.
Six months ago I was fortunate to sit in on a small-group lecture led
by one of the world's top nutrigenomics researchers, Dr. Ahmed El-
Sohemy.
When I heard Dr. El-Sohemy speak, I realized that I was wrong.
With the completion of the human genome project and the latest
nutritional science, it's clear that nutrigenomics is no longer the
future of medicine. It's here today. And it's being applied by cutting-
edge health experts everyday.
As I sat in the audience, my neurons were firing like a fourth of July
light show. There was so much info flying around that my pen couldn't
move fast enough to keep up. I knew I had to sit down to pick Dr El-
Sohemy's brain.
Here's what came out of our latest conversation.
John Berardi: Dr. El-Sohemy, thanks for agreeing to do this interview.
It's much appreciated and I know everyone reading will be fascinated
by your work.
A few months back, you presented some very interesting data looking at
how genomic information can impact our understanding of nutrition and
nutrient science. In other words, you talked about how our genes can
determine our responses to the food we eat, the supplements we take,
and more.
For those readers unfamiliar with this area of research, can you
briefly describe the field of nutrigenomics?
Dr. Ahmed El-Sohemy: Nutrigenomics, sometimes called nutritional
genomics, investigates how the foods we eat interact with our genes to
affect our health. The questions we typically ask are, "How much of
each nutrient should a particular person consume?" and, "What are the
biological effects of a specific supplement?"
There are basically two approaches that we use to investigate such
questions.
First, we look at how common variations found throughout the human
genome explain individual differences in response to dietary intake.
For example, this area of research explains why some people can eat a
high fat diet and have no problem with their cholesterol levels while
others experience the exact opposite response.
There is the fundamental problem here. The idea that apparently some
people can eat a high fat diet and have no problems and others
experience the opposite, is dead wrong. That concept is false.
The problem is not eating a high fat diet in and of itself. The
problem arises from the quality of the fats in the diet. And the
quality of the carbs and the quality of the proteins.
Aboriginals in Canada historically have been very healthy eating
mostly animal and fish fats in large quantities along with healthy
animal proteins and what little carbs they eat is high quality
wholefood carbs.
If you prefer to eat highly processed vegetable oils and margarines,
you can eat as little or as much as you want and you will still be
unhealthy. For one, you will be deficient of the healthy animal-source
fats (omega 3, 6, etc.) themselves, and you will be deficient of fat
soluble vitamins, A, D, E and K.
If you chose to make most of your diet from processed low-fat cereal
derived crap, you will be deficient in the fat nutrients and most of
the water soluble vitamins. Not to mention the animal sourced
collagen.
The whole saturated fat nonsense is nonsense.
.
- References:
- Applied Nutrigenomics
- From: Taka
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