Re: Vitamin c may have undesired action



On Oct 1, 11:39 pm, "John Hasenkam" <jo...@xxxxxxxxxxxxxxxx> wrote:
There is little point in taking vitamin C supplements.

This is to over estimate the effect of diminishing uptake. While true
absorption does drop off, one gets the majority of 300 milligram dose.
And it possible to repeat this more than once per day.

Another aspect of taking ascorbic acid is take it should be taken
with quercetin and rutin. Even the term vitamin to describer AA
reflects
a shortcoming in understand its nature.

What follows are some recent published comments on the subject
of ascorbic acid and the full papers are available
for these three if I recall correctly.

ndian J Med Res. 2007 Nov;126(5):471-4.

Effect of vitamin C on blood glucose,
serum lipids & serum insulin in type 2
diabetes patients.

Afkhami-Ardekani M, Shojaoddiny-Ardekani A.

Diabetes Research Center, S
hahid Sadoughi University of Medical Sciences & Health
Services, Yazd, Iran.
afkhamiam@xxxxxxxxx

BACKGROUND & OBJECTIVE:
Diabetes mellitus is one of the most common metabolic
disorders that causes micro- and macro-vascular complications. Because
of
additive effects of hyperglycaemia and hyperlipidaemia for
cardiovascular
diseases, lipid abnormalities should be evaluated in diabetes. As
vitamin C is
known for its beneficial effects on serum lipids and glycated
haemoglobin
(HbA1c), we evaluated the effect of different doses of vitamin C on
blood
glucose, serum lipids and serum insulin in individuals with type 2
diabetes
mellitus.

METHODS:
A total of 84 patients with type 2 diabetes referred to Yazd
Diabetes Research Center, Iran, were included in the study. They
received
randomly either 500 mg or 1000 mg daily of vitamin C for six weeks.
Fasting blood
sugar (FBS), triglyceride (TG), total cholesterol (TC), low and high
density
lipoprotein (LDL, HDL), glycated haemoglobin HbA(Ic) and serum insulin
were
measured before and after vitamin C consumption and the results were
analyzed.

RESULTS:
A significant decrease in FBS, TG, LDL, HbA1c and serum insulin was
seen
in the group supplemented with 1000 mg vitamin C. The dose of 500 mg
vitamin C,
however, did not produce any significant change in any of the
parameters studied.

INTERPRETATION & CONCLUSION:
Our results indicate that daily consumption of 1000
mg supplementary vitamin C may be beneficial in decreasing blood
glucose and
lipids in patients with type 2 diabetes and thus reducing the risk of
complications.


PMID: 18160753


Tex Heart Inst J. 2007;34(3):268-74.

Comment in:
Tex Heart Inst J. 2007;34(3):265-7.

Oral ascorbic acid in combination with beta-blockers is
more effective than beta-blockers alone in the prevention
of atrial fibrillation after coronary
artery bypass grafting.

Eslami M, Badkoubeh RS, Mousavi M, Radmehr H, Salehi M,
Tavakoli N, Avadi MR.

Department of Cardiovascular,
Imam Khomeini Hospital,
Tehran University of
Medical Sciences, Tehran 14197-33141, Iran.

Because adrenergic beta antagonists are not sufficient to prevent
atrial
fibrillation after coronary artery bypass grafting, this prospective,
randomized
trial was designed to evaluate the effects of ascorbic acid as an
adjunct to
beta-blockers. Fifty patients formed our ascorbic acid group, and
another 50
patients formed our control group. All patients were older than 50
years, were
scheduled to undergo coronary artery bypass grafting, and had been
treated with
beta-blockers for at least 1 week before surgery. The mean age of the
population
was 60.19+/-7.14 years; 67% of the patients were men. Patients in the
ascorbic
acid group received 2 g of ascorbic acid on the night before the
surgery and 1 g
twice daily for 5 days after surgery. Patients in the control group
received no
ascorbic acid. Patients in both groups continued to receive beta-
blockers after
surgery. Telemetry monitoring was performed in the intensive care
unit, and
Holter monitoring was performed for 4 days thereafter. The incidence
of
postoperative atrial fibrillation was 4% in the ascorbic acid group
and 26% in
the control group (odds ratio, 0.119; 95% confidence interval,
0.025-0.558, P =
0.002). We conclude that ascorbic acid is effective, in addition to
being
well-tolerated and relatively safe. Therefore, it can be prescribed as
an adjunct
to beta-blockers for the prophylaxis of post-bypass atrial
fibrillation.

PMCID: PMC1995047
PMID: 17948074




1: Exp Biol Med (Maywood). 2007 Jul;232(7):847-51.

Ascorbic acid role in containment of the world avian flu pandemic.

Ely JT.

Radiation Studies,
University of Washington,
Seattle, Washington 98195, USA.
ely@xxxxxxxxxxxxxxxx

In this Comment, the ultimate intent is to increase survival of the
anticipated
global flu pandemic. The apparent failure of "medicine" to provide a
completely
understood and logically based biochemical prevention and treatment
for all
influenzas (and many other viral diseases) may be an unavoidable
result of the
evolving complexity of the H5N1 virus. However, clinical experience
cited in all
accounts, including the 2003 to 2006 period, suggest that: (i)
ascorbic acid is
not being administered to humans infected or at risk for influenza,
and (ii)
ascorbic acid is (mistakenly) believed to be a vitamin ("vitamin C").
Proper use
of ascorbic acid as described here could provide effective containment
for the
flu pandemic.


PMID: 17609500





The body simply will
not absorb it. However, there are a number of studies indicating injecting
vitamin C, to overcome the but absorption problem, can be effective against
some cancers. At very high doses, vitamin C becomes a pro-oxidant,
particularly in the presence of free iron(haber-weiss).

John.http://healthycuriousity.blogspot.com/2008/10/vitamin-c-may-inhibit-c...

<trigonometry1...@xxxxxxxxx> wrote in message

news:d4c76e3b-88c8-4481-a34e-9b598ce77508@xxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
On Oct 1, 6:19 am, anonym...@xxxxxxxxxxxxxxxx wrote:

http://www.eurekalert.org/pub_releases/2008-10/aafc-vcs092308.php

PHILADELPHIA In pre-clinical studies, vitamin C appears to
substantially reduce the effectiveness of anticancer drugs, say
researchers at Memorial Sloan-Kettering Cancer Center.

Just remember, most people aren't being treated for cancer.
This why the Doctors should ask patients about their vitamin
regimens and patients should tell them.

.



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