Re: Omega-3 (ALA) and prostate cancer

On Nov 4, 8:52 pm, "trigonometry1...@xxxxxxxxx |"
<trigonometry1...@xxxxxxxxx> wrote:
Taka wrote:
Prostaglandins Leukot Essent Fatty Acids. 2008 Oct 22. [Epub ahead of
print]

Omega-3 PUFA: Good or bad for prostate cancer?

Brouwer IA.
Department of Nutrition and Health, Institute of Health Sciences, VU
University Amsterdam, De Boelelaan 1085, 1081 HV Amsterdam, The
Netherlands.

INTRODUCTION: The objective of this meta-analysis was to estimate
quantitatively the associations between intake or status of omega-3
polyunsaturated (omega-3 PUFA) fatty acids and occurrence of prostate
cancer in observational studies in humans. METHODS: We combined risk
estimates across studies using random-effects models. RESULTS: The
combined estimate showed an increased risk of prostate cancer in men
with a high intake or blood level of alpha-linolenic acid (ALA)
(combined relative risk (RR) 1.36; 95% CI 1.08-1.70). The association
is stronger in the case-control studies (RR 1.84; 95% CI 1.04-3.25)
than in the prospective studies (RR 1.10; 0.91-1.32). Ecosapentaenoic
acid (EPA) and docosahexaenoic acid (DHA) were not significantly
associated with prostate cancer. DISCUSSION: The association between
high intake of ALA and prostate cancer is of concern and needs further
study. However, the fact that the prospective studies do not show a
clear association makes a true effect of intake of ALA on prostate
cancer less likely.
PMID: 18951003

Isn't the conversion percentage of ALA to the metabolically active
omega 3 fatty acids only about 5 %?

This may be telling us something about the true body needs for the
Omega-3 "EFAs". The body would convert only as much as it needs so
the remaining 95% ALA is not needed and only puts strain on the lipid
peroxide detoxification metabolism and if this fails prostate cancer
appears. When the body needs more Omega-3s like during the pregnancy
it upregulates the conversion of ALA to EPA/DHA.

Taka
.

Relevant Pages

  • Certain Omega-3s May Reduce Prostate Cancer Risk
    ... eicosapentaenoic acid and docosahexaenoic acid may have a ... reduced risk of prostate cancer, ... Researchers evaluated the association between dietary intake of ALA, ... who were free from prostate cancer at the start of the study. ...
    (sci.med.prostate.cancer)
  • Certain Omega-3s May Reduce Prostate Cancer Risk
    ... eicosapentaenoic acid and docosahexaenoic acid may have a ... reduced risk of prostate cancer, ... Researchers evaluated the association between dietary intake of ALA, ... who were free from prostate cancer at the start of the study. ...
    (misc.fitness.weights)
  • Re: Omega-3 (ALA) and prostate cancer
    ... Omega-3 PUFA: Good or bad for prostate cancer? ... acid and docosahexaenoic acid were not significantly ... high intake of ALA and prostate cancer is of concern and needs further ...
    (sci.med.nutrition)
  • Re: Omega-3 is NOT a Cancer or Heart-Disease Preventive
    ... those studies showing ALA is associated with more invasive prostate ... Dietary alpha-linolenic acid is associated with reduced risk of fatal ... occurrence of prostate cancer in observational studies. ...
    (sci.med.nutrition)
  • Re: Red Meat NO GOOD, Veggies no protection.... NOW WHAT?
    ... associated with men's risk of developing advanced prostate cancer. ... That's because, believe it or not, they said red meat is "relatively high" in ... Omega-3 ALA and low in the primary essential Omega-6 - linoleic acid. ...
    (sci.med.cardiology)