Re: Omega-3: The killer oils
- From: Taka <taka0038@xxxxxxxxx>
- Date: Thu, 4 Dec 2008 00:34:13 -0800 (PST)
Dear Doctor,
I walked into a health food store not long ago for the first time
in many years. I cannot say I was surprised by what I saw, but the
sheer magnitude of the promotional HYPE made me feel as if I were
being propositioned with the enticing promises of a classic ...
SWEET-TALKING SNAKE OIL SALESMAN.
Fully one fourth of the store was dominated by Soy Death as he
loudly proclaimed his power to prevent or cure every malady known to
humankind. One entire end of the store featured She-Beast
Phytoestrogen as she sang her siren song of cures for the very
conditions caused by excess estrogen. But the most captivating song
and dance of all was performed by none other than Omega 3 PUFA, winner
of the decade’s Pseudo-Science Award, who was seen masterfully
manipulating people in every section of the store.
WHAT HAPPENED TO THE GOOD OLD DAYS ...
when health food stores were dominated by comparatively benign
villains such as health food store cookies, juices, and mega dose
vitamin supplements? In days of old, health food store customers were
victims only of their own stupidity. Now, in blissful ignorance, they
are self-destructing under the influence of a deadly, powerful,
propaganda machine.
My point is that now there is so much money to be made in soy,
phytoestrogens, and omega 3 fatty acids, that the little cult of
people who created the health food industry as a grass roots movement,
have been completely displaced in their own industry by Agri-business.
Only by spending billions of dollars has Agri-business been able to
convince us that soy, phytoestrogens, and omega 3 (as well as omega 6)
fatty acids are good for us, when in fact ...
THEY ARE THE MOST DEADLY OF ANTI-METABOLITES.
While introducing you to the oxidative free radical damage and
premature aging caused by omega 3 fatty acids, I commented in last
month’s Letter, “I realize how thoroughly effective the propaganda in
favor of omega 3 fatty acids (just as for the omega 6 fatty acids
before them) has been. That is precisely why this Letter is so
important to you. You and your patients have been so effectively
brainwashed regarding omega 3 fatty acids that you will need at least
two issues of your NUTRI-SPEC Letter, offering dozens of references
from the scientific literature, to help you see the truth.”
I explained that even I had been snookered to some degree by the
“research” supporting the clinical use of ALA, EPA, and DHA
supplementation. For more than 25 years I fooled around with using
omega 3 fatty acids for both my prostaglandin imbalance patients and
my anaerobic imbalance patients. Now that I know better, I am
determined to give you the truth about the deadly omega 3 fatty acids,
just as we have given you in years past the complete case against the
very convincing and popularly accepted soy and estrogen propaganda.
The problem with my clinical experimentation with fish oil
supplements was that I could honestly never see any evidence, either
objective or subjective, that the supplementation was doing any good.
But I would no sooner stop recommending EPA and DHA than I would find
a research study in the literature compelling me to once again work at
finding a way to make fish oil supplements work. Finally, after more
than 20 years of on-again, off-again use of fish oil supplements, two
things happened. First, the evidence from the scientific literature
revealing the damages of fish oil began to out-weigh evidence for its
benefits. Second, I did extensive experimentation on various ways of
dosing EPA and DHA on myself, with careful monitoring of objective and
subjective results. From the anti-fish oil evidence in the literature
I got the idea to only use EPA and DHA supplementation on a temporary
basis for new patients in an effort to control prostaglandin-related
symptoms. From the experimentation done on myself, all I got was a
forehead full of unsightly age spots.
Several months ago, after years of going in circles regarding omega
3 fatty acids, I finally did what I should have done years earlier -
an exhaustive literature search on ALA, EPA, and DHA. The results of
that search left me red faced with embarrassment. All I can do now is
face the truth, and pass that truth along to you. And that truth is,
quite simply, that ...
OMEGA 3 OILS ARE EVEN MORE DAMAGING
THAN OMEGA 6 OILS.
The only reason we do not see more pathology associated with
omega 3 fatty acids is that quantitatively they exist in our diets in
only a tiny fraction of the omega 6 fatty acids we consume.
How are ALA, EPA, and DHA so damaging? Recall from last month’s
Letter the three ways by which omega 6 fatty acids destroy our health:
by lipid peroxidation
by prostaglandin formation
by the formation of trans-isomers and other unnatural fatty acids
Omega 3 fatty acids are guilty of only one of these three sins
--- the acceleration of lipid peroxidation. But the omega 3 fatty
acids are far more subject to oxidative free radical damage than are
the omega 6 fatty acids. Fish oils not only rapidly destroy vitamin E
in the body, but they spontaneously oxidize with incredible speed,
even before they reach the blood stream. In undergoing such rapid
oxidation, they form strange and ultra-pathological fatty acids, much
as the omega 6 fatty acids do in response to heat.
I will begin this exposé of omega 3 PUFAs by showing just how
vulnerable they are to oxidation, and how easily they cause lipid
peroxidation damage in the body. That introduction will be followed by
a more detailed description of how these PUFAs specifically cause
damage to the brain, liver, skin, thymus, spleen, and heart, and
accelerate the progression of diseases such as atherosclerosis,
diabetes, stroke, and cancer.
LIPID PEROXIDATIVE DAMAGE:
The first thing to understand regarding the oxidation of omega 3
oils, is that these oils are so unstable that they begin to
spontaneously oxidize even before they reach the blood stream.
Fish oil is so subject to oxidation that, without antioxidants,
it is almost totally degraded within 48 hours; no amount of added
antioxidant prevents considerable degradation. That spontaneous
oxidation is what made fish oils useful as varnish and in paint, but
it is what also causes them to induce catabolic oxidative damage to
tissues.
J Nutr. 1988 Apr;118(4):425-6. Rapid auto-oxidation of fish oil in
diets without added antioxidants. Fritsche, et al.
J Nutr. 1992 Nov; 122(11):2190-5. Lipid peroxidation products are
elevated in fish oil diets even in the presence of added antioxidants.
Gonzalez, et al.
Adv Exp Med Biol. 1991;289:255-68. Dietary omega 3 polyunsaturated
fatty acids of fish oils, auto-oxidation ex vivo and peroxidation in
vivo: implications. Kinsella J.
The degenerative diseases are all associated to some degree with
lipid peroxidation. Alzheimer’s Disease, various forms of arthritis,
liver disease, retinal degeneration, epilepsy, AIDS, diabetes, and
vascular disease, to name a few, all involve breakdown products of
PUFAs. The products of PUFA oxidation include acrolein,
malondialdehyde, hydroxynonenal, crotonaldehyde, neuroprostanes, and
countless other derivatives of fatty acid oxidation. These are the
substances you are measuring in the urine with your NUTRI-SPEC surface
tension test.
One of the most demonstrable pathological effects of all PUFAs,
both omega 6 and omega 3, is ...
THE FORMATION OF LIPOFUSCIN
(ALSO KNOWN AS “AGE PIGMENT,” OR “LIVER SPOTS”) ...
resulting from oxidative free radical damage, particularly when
accompanied by insufficient vitamin E. Lipofuscin, or ceroid pigment,
does not just form in the skin, it forms simultaneously in the brain.
Associated with the formation of lipofuscin, PUFAs were discovered
decades ago to cause degeneration of the gonads, and the brain. In
fact, it was the protection against lipofuscin formation that allowed
early researchers to understand that the essential role of vitamin E
is as an antioxidant.
In their 1968 edition of Present Knowledge in Nutrition, Hartroft
and Porta showed that adequate saturated fat (meat, poultry, eggs,
cheese, coconut oil, and palm oil) in the diet actually protects
against the formation of the lipofuscin caused by unsaturated fat.
Specifically, they showed that age pigment is produced in proportion
to the ratio of oxidants to anti-oxidants, multiplied by the ratio of
unsaturated fats to saturated fats. Other studies demonstrate that
ultra violet light induces peroxidation in unsaturated fats, but not
saturated fats, and this occurs in the skin. The unsaturated fat in
the skin is a major target for the aging and carcinogenic effects of
ultra violet light. (As a side note, other experiments have shown that
the amount of unsaturated oil in the diet strongly affects the rate at
which the skin develops wrinkles. How ludicrous is it to use skin
lotions made from vegetable oils?!)
Many studies have shown that after ingestion of omega 3 fatty
acids the end products of oxidative lipid damage increase
substantially. 4-hydroxynonenol is a particularly pathological end
product of omega 3 PUFA oxidation. Malondialdehyde is shown to
increase substantially in the body following ingestion of concentrated
omega 3 fatty acids, but also from ingestion of whole cod liver oil.
Oxidative end products after omega 3 PUFA ingestion are shown to be
associated with an acceleration of atherosclerosis development, and
also with increased oxidative damage in bone marrow DNA in rats.
Dietary polyunsaturates poison several mitochondrial functions,
including cytochrome oxidase.
Borst, P., et al. “Uncoupling Action Of Long Chain Fatty Acids,”
Biochem. Bioph. Acta, 62, 509-18, 1962.
PUFAs stimulate excess production of prostaglandins –
contributing to inflammatory joint disease, osteoporosis, immuno-
suppression, and fluid retention.
Johnston, P. “Dietary Fat, Eicosanoids, and Immunity,” Advances In
Lipid Research, 21, 103-41, 1985.
Polyunsaturates distort fluid movements within and between cells,
and thus negatively impact intercellular communication. Excess
unsaturated fats retard cellular development and/or accelerate cell
death.
Lipids. 22(6), 445-54, 1987. “Effect of fatty acids on junctional
communication: Possible role in tumor promotion by dietary
polyunsaturated fat,” Aylsworth, C.F. et al.
Antioxid Redox Signal. 1999 Fall;1(3):255-84. 4-Hydroxynonenal as a
biological signal: molecular basis and pathophysiological
implications. Parola, et al.
Lipids. 1988 Apr;23(4):370-1. Malondialdehyde excretion by subjects
consuming cod liver oil vs a concentrate of omega 3 fatty acids.
Piche, et al.
Neurobiol Aging. 2005 Apr;26(4):465-74. Immuno chemical cross
reactivity of antibodies specific for “advanced glycation end
products” with “advanced lipoxidation end products”. Richter, et al.
Atherosclerosis. 1997 Nov;Vol.135, no. 1, pp.1-7. Oxidized cholesterol
in the diet accelerates the development of atherosclerosis in LDL
receptor deficient and apolipo protein e-deficient mice. Staprans, et
al.
J Nutr. 2000 Dec;130(12):3028-33. Polyunsaturated omega 3 fatty acids
susceptible to peroxidation are increased in plasma and tissue lipids
of rats fed DHA-containing oils.
Free Radic Res. 2001 Apr;34(4): 427-35. DHA supplementation increases
oxidative damage in bone marrow DNA in rats and the relation to
antioxidant vitamins. Umegaki, et al.
That concludes your introduction to the catabolic oxidative
damage done by ALA, EPA, and DHA supplementation. Next month you will
learn the details of the immuno-suppressive damage, brain damage,
cardiovascular disease, and diabetes caused by omega 3 PUFAs. You must
save your family and patients from the snake oil salesman. He has sold
his remedy to literally millions of unsuspecting victims using pseudo-
science to strengthen his pitch. Armed with real scientific truth, you
are in a position to protect everyone you know. Take it as your duty.
[Agri-business is now putting DHA in baby formula, even though honest
research shows that PUFAs impair infant brain development (while
saturated fats are essential for normal brain development and nerve
myelination), and, omega 3 fatty acids increase the incidence of
allergies in infants.]
Remember the formula:
Health = (anti-oxidants/oxidants) x (saturated fats/PUFAs)
The means to increase vital reserves are yours to offer your
patients. You can translate the above formula:
Health = [(OXY POWER + GO POWER + OXY A+ or D+)/(STRESS)] x [NSFD]
All your patients are suffering from oxidative stress --- and YOU
have the worlds most powerful anti-oxidant nutrition plan.
SOURCE: http://www.nutri-spec.net/nl/2005-12.html
.
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