Re: Autism / oxidative stress

From: doe (ironjustice_at_aol.comdoe)
Date: 06/21/04


Date: 21 Jun 2004 16:45:00 GMT


>Subject: Re: Autism / oxidative stress
>From: dgoncz@aol.com.bat.exe ( Doug Goncz )
>Date: 6/21/2004 5:00 AM Mountain Daylight Time
>Message-id: <20040621070034.23916.00000378@mb-m28.aol.com>
>
>Wow.
>
>As a schizophrenic, I experience some autism. The old "four A's" of
>schizophrenia are: autism, affect, ambivalence, and associations. These are
>replaced in modern nursing school by alogia, anhedonia, affect, and
>association.
>
>I am brilliantly verbal, and yet autistic. This is no contradiction. What
>happened to me caused me to give up my faith in language, and so develop a
>pattern of highly intellectuallized, yet ineffective speech. I swear, I can
>sit
>in "talk therapy" all day and share affective speech (emotionally honest
>speech) and intellectualize around it, but it does me no good. My speech is
>not
>substantially _effective_. That is, talking about my emotions doesn't change
>my
>life. And as for making plans with speech, that is, considering anything more
>substantial than when is my next appointment, I am paralyzed, mute. Yet the
>therapists I am with do not notice this. They think, he must be able to talk
>to
>anybody about anything, and so, doesn't need help.
>
>But I can't. It's as if I'm mute. I've lost the critical belief that language
>_does some good_, that's it's useful.
>
>So what I am looking for is a diagnosis of autism secondary to schizophrenia,
>and treatement with a speech language pathologist operating at a very
>challenging level.
>
>How does this sound?
>
>Thanks, interesting article and I will ask my psychiatrist to interpret it.
>Perhaps she can test for:
>
>>red blood cells
>>thiobarbituric acid-reactive substances (TBARS) levels, and superoxide
>>dismutase (SOD), catalase (CAT), adenosine deaminase (ADA) and xanthine
>>oxidase
>>(XO) activities
>
>and determine if there is
>
>>lipid peroxidation
>

If you have schizophrenia they have shown lipid peroxidation / oxidative stress
TO BE involved ..

I've questioned Dr. Hoffer as to his work with B vitamins and schizophrenia and
pointed out to him how it is KNOWN iron overload induces schizophrenia and
asked him whether he thought the B vitamins might be just simply chelating the
iron in the body ..

B vitamins are 'argued' to be antioxidants and this .. discrepency may arrive
by the fact an antioxidant seems to be classified as a 'quencher' OF free
radicals or a 'binder/chelator' .. of .. the free radical .. creator.

http://tinyurl.com/2qlyl

<<snip>>
In addition to increased oxidative stress, altered immune function may also be
responsible for increased phospholipase activities.

PMID: 15006493 [PubMed - indexed for MEDLINE]

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