Immune modulation therapy, latest treatment for people with chronic heart failure

From: Dr. Jai Maharaj (usenet_at_mantra.com)
Date: 06/30/04


Date: Wed, 30 Jun 2004 10:09:28 GMT

Immune modulation therapy, latest treatment for people
with chronic heart failure

Posted By: News-Medical in Medical Procedure News
Published: Tuesday, 29-Jun-2004

Here is the latest treatment for people with chronic
heart failure: a nurse draws blood from the patient, runs
that blood through a machine, superheating and
"stressing" the blood, and then, injects it back into the
patient.

It sounds like science fiction -- and too simple to be
true. But that is exactly what cardiologists at the
University of Calgary Faculty of Medicine are doing in a
clinical trial launched today.

The ACCLAIM study is a double-blind, Phase 3 clinical
trial enrolling 2000 people with chronic heart failure
across North America. Clinical research sites include
Sacramento, Montreal, Dallas, Cleveland, Boston, and
Calgary.

"We cardiologists have recently come to understand that
inflammation plays a pivotal role in the development and
progression of heart failure," says Dr. Debra Isaac,
associate clinical professor of cardiology, U of C
Faculty of Medicine. "This procedure targets chronic
inflammation by kick-starting the immune system's own
anti-inflammatory response."

The procedure, known as immune modulation therapy,
involves the following: a nurse takes 10 cc's (about 2
teaspoons) of blood from a patient, and puts that blood
into a specialized machine that applies stresses: heat,
oxidation, and UV light. When white blood cells
experience this stress, they begin to die. The nurse then
re-injects that blood back into the patient's leg muscle.
The dying cells trigger an anti-inflammatory reaction in
the patient, inducing his/her body to boost its own anti-
inflammatory processes.

"It is critical that we slow down the inflammatory
process that is toxic to the heart," says Dr. Jean
Rouleau, dean, Faculty of Medicine, Université de
Montréal, and principal investigator of the study for
Canada. "Our hope is that this potential treatment can
alleviate the serious side-effects of chronic heart
failure, and treat the long-term damage being caused by
the disease."

Phase 2 clinical trials found that this procedure was
beneficial to a significant number of patients, resulting
in fewer hospitalizations, better quality of life,
improved clinical status, and fewer deaths due to the
devastating effects of heart failure.

Dr. Isaac, principal investigator of ACCLAIM in Calgary,
and director, cardiac transplantation program, Calgary
Health Region, is aiming to recruit 30 people who will
undergo the 20-minute procedure on an outpatient basis
once a month for 2 years.

http://www.ucalgary.ca

More at:
http://www.news-medical.net/?id=2916

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The terrorist mission of Jesus stated in the Christian bible:

     "Think not that I am come to send peace on earth:
I came not so send peace, but a sword.
     "For I am come to set a man at variance against his
father, and the daughter against her mother, and the
daughter in law against her mother in law.
     "And a man's foes shall be they of his own
household.
 - Matthew 10:34-36.

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