Re: Questions: Angiogenesis in Cancer
- From: "tech27" <tech27@xxxxxxxxxxxxxxxxxxx>
- Date: Wed, 22 Jun 2005 23:55:04 -0400
>From what I've learned antiogenesis is not related to any other system
except that it serves to provide nourishment to the cancer site. At the same
time, this main "mass" produces anti-angiogenesis compounds which prevent
other sites from "robbing" the primary site of blood flow/nutrients. It has
been observed that in many case removal of the primary mass, and it's
anit-angiogenesis function, allows other sites to become more active.
This reminded me of things my parents would say decades ago about people
they knew who had cancer, things like "Oh, as soon as they removed "the
cancer" it spread all over." etc. They believed that the surgery cause the
cancer to spread because it had been disturbed. Interesting.
"kumar" <lordshiva5753@xxxxxxxxxxxxxx> wrote in message
news:1119155754.510590.58350@xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
> Hello,
>
>
> I have following thoughts about Angiogenesis & request you to awnser
> these after serious thinking:-
>
>
> When cancer is in tumor stage it is considered that cancer cell can
> encourage Angiogenesis for their nutrition, multiplication & spread.
> But, I think that there can be two conditions related to it.
>
>
> 1.On naturally improved/biologically medicated immunity:- when a person
> gets cancer, our immune system should be trying to kill/correct the
> cabcer cells. But when our immune system couldn't handle these due to
> required immune strength, cancer cells then may opt to arrest/encapsule
> these in tumor etc.in cansiderations of (a)to starve them by inhibiting
> blood supply or their respiration or nutrients (b)to restrict & resist
> there growth & spread (c)to hold them in encapsuled/tumor state &
> pursue to improve the immunity or wait for right time/immunity level,
> when it can handle/kill thise cancer cells.
>
>
> 2.On weakening of immunity (natural or otherwise):- It may encourage
> cancer cells to multiply & spread as progress of disease. I can't say
> whether it can be Angiogenesis oriented or not?
>
>
> Now my questions are:
>
>
> 1.Are cancer cells or other disease causing agents in tumor/latencies
> capable of encouraging Angiogenesis, in view of that it os our body's
> immune defence mechanism?
>
>
> 2. Can it be thought/possible that Angiogenesis is an immune defence
> mechanism "On naturally improved/biologically medicated immunity" as I
> described above, either to transport immune agents in tumor to kill
> them OR to encourage them to resurface/take out from tumor for exposure
> to immune system for killing them?
>
>
> 3. Can it be also thought that Angiogenesis may not be possible "On
> weakening of immunity (natural or otherwise)" as I described above?
>
>
> In short, can it be dynamically thought that, somewhat spread or
> resurfacing of cancer cells & Angiogenesis can occur on improved
> immunity to kill those as a "direction towords cure" instead of
> "direction towords progress of disease"? This aspects may also be
> thought for other latencies.
>
> I think it is nowhere clearly mentioned, what happens when a person
> with latent infections or cancer strengthened his immune system,
> naturally, at some later date? Can it handle/cure latencies & cancer?
>
> Best wishes.
>
.
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