Re: of plague dogs and cryonics

>>The first one and the third one are not really of much clinical
significance *except* insofar as they suggest that cooling *before*
cardiac arrest/VF occurs protects the brain. <<

COMMENT:

The third trial was merely an animal model showing it's possible to
produce hypothermia very rapidly. That can be done also AFTER a cardiac
arrest, provided that a perfusing rhythm has been established.

Yes, the first abstract is looking at hypothermia induced before
arrest.

The second is a metaanalysis of three trials of INDUCED post
resuscitation hypothermia in humans. In all of these hypothermia was
INDUCED after the resuscitationed patient arrived at the hospital. If
you read the individual studies, you will see that patient admission
temp is a controlled variable. It doesn't differ between treatment and
control groups PRIOR to randomization to post resuscitation
hypothermia. So temperature during arrest is not a factor. Nor is
hypothermia a cause of arrest in any of these cases--- those were
excluded. These are primary cardiac arrest cases. Many from heart
attack and surely most form primary cardiac diseases. The point of the
study is that humans benefit from post arrest cooling just as animals
do (and there are many animal trials of POST resuscitation induced
hypothermia if you'd like me to post some).

>>Have you given up on your cryonics work? Is the real end goal of your research no longer resusuitation after years/decades/centuries of suspended animation through freezing? <<

COMMENT:

Well, that's one of my really LONG TERM goals :). But most of those
advances will be made by the organ preservation people, at temperatures
far below those at which I work. I'm interested in taking off 5 degrees
C, really, really fast.

SBH

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