help understanding lymphoma

Hi,

I'm hoping someone here can help me decipher some of the finer points of
Burkitt's diagnosis for a nursing school clinical assignment. The points
I'm stuck on include:

I know what "FISH" is (fluoroescence in-situ hybridization) but not
"interface" FISH. How would immunoglobulin heavy chains fuse, and if they
did, how would that be significant in Burkitt's?

The original phrase was: (positive for) "IgH fusion" (by interface FISH)

Then there's this: While I understand the definitions of all of the
following terms, I don't understand why it's important.

"High-intensity monoclonal surface IgG of lambda isotype."

Any help will be greatly appreciated.

Many thanks, --Patti


.

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