Re: Questions on Glucose Oxidation


"gowentgone" <andylcy@xxxxxxxxx> wrote in message
news:1141718725.784598.109460@xxxxxxxxxxxxxxxxxxxxxxxxxxxxxxx
So, for diabetic patients, decrease in rate of glucose oxidation is the
cause of increase in blood glucose level.

Because it can't get into the cell to be oxidized.

But after meal, blood glucose
level rises and causes an increase in rate of glucose oxidation.

No. The cell is starving so the body is producing even more glucose apart
from what you are eating and it all stays outside the cell and thus it is
not getting oxidized.
The increase in blood sugar in a diabetic is a result of a decrease rate of
intake of intracellular glucose and the production of new glucose from body
stores in addition to fatty breakdown.

I am
confused with the logic. Could you explain a bit about the relationship?


The amount of glucose oxidation within the cell is directly proportional to
the amount of insulin and insulin receptors outside of the cell. If insulin
is high then glucose moves inside the cell and can be oxidized. If insulin
is low then it stays outside the cell and glucose oxidization is unavailable
to the cell.


.

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