Re: Mycophenolate Mofetil Reduces Erythropoiesis
- From: "ironjustice@xxxxxxx" <ironjustice@xxxxxxx>
- Date: Sun, 11 Nov 2007 19:02:24 -0800
On Nov 10, 12:01 pm, " Rick EN. Bocker"
<RickENBockerNoS...@xxxxxxxxxxxxxxxxxxx> wrote:"The research was
supported by Aspreva Pharmacuticals"
a small, meaningless study.
Have to be repeated in large cohort multi-center trials to eliminate
possible bias <<
Buuuut .. if you WERE .. **looking** / keeping your eyes OPEN
**because** YOU .. personally are / were AFFECTED by this ..
problem .. one might look at it more with a .. cuphalffull / hope ..
and follow UP on .. my .. observation that .. connective tissue
disease .. "seems to be somehow connected to possible .. possible ..
increased red blood cell production" .. then one might attempt to
follow up ON this "slim lead" .. because .. ? .. you have no hope ..
IE: no know cause no good treatment.
Sooo .. where to go from there .. ? / as opposed to YOUR .. sit and
wait for **them** to decide whether this drug will make enough money
FOR them to EVEN .. bother .. ?
Type in 'connective tissue disease' .. then look for what drugs are
BEING used THERE and then seeing IF those types or maybe even
SPECIFICALLY that drug IS **also** being used to treat increased red
blood cell production / erythrocytosis / hemochromatosis /
polycythemia OR maybe even lupus ALREADY ..?
Who loves ya.
Tom
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...
ironjustice wrote:
Therapy Effective for Reducing Lupus Flares
Newswise - Mayo Clinic researchers have shown that an
immunosuppressive drug used in organ transplant cases is effective in
reducing flare-ups in patients with systemic lupus erythematosus
(SLE). SLE results in inflammation of connective tissues and can
involve the skin, joints and kidneys. Its cause is unknown. The
findings were announced today at the annual meeting of the American
College of Rheumatology in Boston.
"Our findings show this therapy reduces lupus flares overall and is
especially effective in reducing severe flares by roughly half," says
Mayo rheumatologist Kevin Moder, M.D., who led the research.
The research team evaluated mycophenolate mofetil (MMF) to see if it
would reduce the number of flares in SLE, which is both chronic and
relapsing.
In the retrospective study, researchers studied 88 patients treated
with MMF at Mayo Clinic over a two-year period. They also studied
patient histories and data on lupus flares going back two years. The
patients, whose average age was 44, had lupus for an average of 10
years. The majority of participants were women.
Before the MMF, lupus flares in the group totaled 155 compared to 99
after treatment. For severe flares, the improvement was even more
dramatic, from 98 to 54.
Even with a significant reduction in use of the anti-inflammatory drug
prednisone -- which many were also taking -- the MMF treatment
significantly reduced flares.
The research was supported by Aspreva Pharmacuticals. Others on the
Mayo Clinic team included Carlotta Nannini, M.D.; Cynthia Crowson; and
Eric Matteson, M.D.
"The research was supported by Aspreva Pharmacuticals"
a small, meaningless study.
Have to be repeated in large cohort multi-center trials to eliminate possible bias- Hide quoted text -
- Show quoted text -
.
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