What kind of anemia is this?
- From: biggero <biggero@xxxxxxxxxxxxxx>
- Date: Sat, 19 Apr 2008 05:54:34 -0700 (PDT)
Here are the results of my recent lab tests:
RBC: 5.75*10^12 / L (normal 4.1 - 6)
HCT: 45.6 % (normal 40 - 54)
MCV: 79.3 (normal 79 - 96)
MCH: 25.8 (normal 26 - 32) - LOW
RDW: 15,6 (normal 11.5-14.5%)
Reticulocytes: 1.89 % (normal 0.5 - 2.0 %)
but:
Reticulocytes count = Reticulocytes * RBC =
1.89 % * 5.75*10^12 / L = 108.6*10^9/L (normal 25-75*10^9/L) - HIGH
ESR = 1 mm/h
CRP = never increased, always close to 0
These above are typical results for me after winter.
But after summer, when I have some physical activity the results are
more like sth like that:
RBC: 6.21 (normal: 4.1 - 6.0) - HIGH
MCV: 75.2 (normal: 80-99) - LOW
MCH: 25.1 (normal: 27-35) - LOW
HCT: 46.7 (normal: 40 - 54)
My GP never cared about these results - she only asked if it runs in
my family.
Yes, it runs - my mother and brother have similar results. So, it's OK
- she said and clearly she was completely wrong, because if it runs in
my family this means sth completely opposite - it may be hereditary.
I also had theese tests done, and that's what concerned me.
Serum Iron: 177 mcg/dl (normal 50-120) - HIGH (repeated twice with
the same result)
TIBC: 484 mcg/dl (normal 250 - 450) - HIGH
Ferritin: 128 ng/ml (normal 30-400)
3 years ago I also had serrum iron done and it was 3 times higher than
normal - and this GP of mine also did not care...
So, what is the conclusion?
*It is rather not iron deficiency anemia (high iron and normal
ferritin level).
*It is rather not chronic disease anemia (I had blood test 12 years
ago, when I felt OK, and the results were exactly the same. Now I am
28, so then I was not able to interpret the reslults).
*So it looks rather like hemolytic anemia (or other of this kind -
thallassemia...).
Anyway it looks like it is hereditary.
Erthropesis is normal (increased RBC in the summer, when I excercise),
but when I have increased RBC, even more erythrocytes are destroyed,
what results in even lower MCV and MCH.
It looks like there is high iron turnover (high, serum iron and normal
ferritin). One thing that doesn't match is TIBC - it should be normal.
I cann't find anywhere, what increased TIBC means in this case. Does
anyone know, if it can be increased, because body just wants to get
rid of excess iron?
If I have increased serum iron, can I have symptoms similar to
hyperchromatosis? Afterall these free radicals caused by iron are
there...? I have joint pain (not arthritic, unknown cause), and
usually I don't feel too well.
What other tests can I do (possibly not very expensive) in order to
have differential diagnosis?
I have to go to hematologist, and I want to go to a good one and this
means waiting 8 weeks.
I might also go somewhere else, and I would rather have some data and
ideas, so that they could not get rid of me that easily.
.
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