Re: Regressing against a proportion?



On Sep 29, 1:19 pm, "hp" <h...@xxxxxx> wrote:
I'm talking to investigators who measure the percent fibrosis of an organ
(between 0 and 100%). They want to compare the effect between treatment
groups; in particular, they would like to see a 20% or better difference.

We can't use logistic regression here, since the outcomes are not zero's or
one's. On the other hand, we cannot quite use linear regression either. I
know that if the sample size is large enough, we can (because of the central
limit theorem); but they're talking about a clinical trial of <100 patients.

a) What is the best method here?

b) How should one go about doing power calculations?

Thanks!

Can't we use test for proportions or ANOVA here?

.



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