Re: Choosing the right method
- From: Frank E Harrell Jr <f.harrell@xxxxxxxxxxxxxx>
- Date: Thu, 04 Aug 2005 11:45:22 -0500
Eric wrote:
Dear all,
A frined of mine, who is ophtalmic surgeon needs to make a study regarding factors affecting a disease. He has got a dataset of appromimately 300 samples (patients), with around 6 or 7 explanatory variables (quantitative or qualitative), and one response variable which is the occuring of the disease.
The problem is that in the dataset the disease is quite rare so that there are few cases of diseases.
What would be the best method in order to discriminate the populations.
We have been suggested : Artificial Neural Net, K nearest neighbors or Decision tree.
Thank you,
Eric
None of those methods will yield reliable predictions. You'll need something like data reduction (e.g. incomplete principal components logistic regression) or penalized maximum likelihood estimation. Above all don't attempt to find which of the variables are 'significant'
Frank .
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