Re: what methods to use?



franco <franco@xxxxxxxx> wrote in news:1177787296.473374.283950
@c35g2000hsg.googlegroups.com:

This is a naive question, not really about specific statistical issues
but more on what procedure to use to investigate something, for me to
learn.
Suppose we have a very large population exposed to a certain product
and suppose that the product can cause a certain specific reaction in
a subpopulation of individuals who are genetically predetermined to
have an interaction with the product (it's a hypothesis we need to
test). Let's say we have indivdual data on various reactions from
those who have been exposed (those reactions may or may not be caused
by the exposure but they happen to occur at various time-points
following the exposure). We have no extra data on the population. We
don't know what is the specific reaction we are looking for (the issue
is to identify it), it could be rare or common. Can we detect such
interactions by using statistical methods? And what would the best
methods be? Thanks.

It is going to be rather difficult to detect an interaction between X and Y
(where X is product and Y is a genetic substrate) in producing Z when you
assume you will not have any information about Y (or know what Z is for
that matter).

--
David Winsemius
.



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