Re: Which test to use?
- From: Jack Tomsky <jtomsky@xxxxxxxxxxxxx>
- Date: Sat, 07 Mar 2009 14:01:00 EST
Hi,
In a research project, 50 rats were made diabetic and
compared with 50
(nonmatched) control rats. Each rat had a measurement
in each of 6
regions in the myocardium (heart). I would like to
compare the
measurements in each of the 6 regions between the
diabetic and control
groups. Of course I could do that by 6 t-tests (one
for each region).
My question, however, is: could there be a test that
allows me to do
an overall comparison between the diabetic and
control groups, for all
regions combined? Something akin to ANOVA?
Thank,
Frank De Geeter, MD, PhD
You can always analyze each region separately with a t test. To exploit the correlations among the six regions to arrive at a single combined test, you can use Hotelling's T-square, which is a multivariate generalization of the Student's t test.
Jack
.
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- Which test to use?
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